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Cholesteryl linoleate

CAS No. 604-33-1

Cholesteryl linoleate ( CE(18:2(9Z12Z));Cholesterol Linoleate;Linoleic Acid cholesteryl ester )

Catalog No. M20009 CAS No. 604-33-1

Cholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via LDL receptor-related protein (LRP) where it undergoes oxidation to form cholesteryl linoleate hydroperoxides.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cholesteryl linoleate
  • Note
    Research use only not for human use.
  • Brief Description
    Cholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via LDL receptor-related protein (LRP) where it undergoes oxidation to form cholesteryl linoleate hydroperoxides.
  • Description
    Cholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via LDL receptor-related protein (LRP) where it undergoes oxidation to form cholesteryl linoleate hydroperoxides.
  • Synonyms
    CE(18:2(9Z12Z));Cholesterol Linoleate;Linoleic Acid cholesteryl ester
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    604-33-1
  • Formula Weight
    649.1
  • Molecular Formula
    C45H76O2
  • Purity
    >98% (HPLC)
  • Solubility
    Chloroform: 10 mg/mL;DMSO: Soluble
  • SMILES
    CCCCC\C=C/C\C=C/CCCCCCCC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CC=C2C1)[C@H](C)CCCC(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Takahashi Y et al. Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase. Biochem Biophys Res Commun. 2005 Dec 9;338(1):128-35.
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